Autism is not only a disease but is turning into a social curse.
We have heard about many neurological disorders, but autism is the only one which does not come with a single disorder. That’s why when a patient is diagnosed with autism, it is found that the patient is suffering from a group of disorders because autism can’t be diagnosed by examining one particular disorder.
That’s the reason why autism is called ASD (Autism Spectrum Disorders).
Some basic symptoms are already pointed out to identify a patient with ASD.
- Social and Behavioral impairment
- Non-verbal interaction
- Lack of eye contact
- Repetitive behavior
with learning disabilities and some common neuropsychiatric disorders.
But if these disorders are not diagnosed at the early stage and neglected, then the autistic symptoms or ASD may turn into another brain disorders (epilepsy) after the puberty stage of patients having ASD.
The very important facts which made this brain disorder a social terror are pointed below.
- It is strongly genetic as it is developed in offspring mainly due to the parental mutated genome transfer in newborn.
- The most vital point for the patients having autism is that, it is an incurable disorder because autism is strongly genetic.
The genetic information resides in the template strand or sense strand of a ds DNA. The ds (double stranded) DNA is responsible for the abnormal protein folding through the process of replication and translation. But if DNAs of the affected tissues are mutated due to the administration of antibiotics along with any intercalating agents or mutagenic substances, then the mutated DNAs are going to produce misfolded proteins or enzymes due to the abnormal genomic expressions.
Besides genomic, proteomic evidences are also strong because 23% of autistic cases are caused due to a group of fetal brain attacking antibodies found in the mothers’ womb. Antibodies are also a group of proteins (immunoglobulin) and are coded by gene/s (HLA).
So, investigation through the proteomic along with genomic studies can help us to unlock the door of this incurable disorder. Genomic isolation (DNA, RNA) from the damaged or impaired tissues of the affected organs can lead us to reach our goal of finding an ultimate cure and therapies rather than behavioral interventions.
Behavioral interventions can improve the social skill impairment to some extend but these interventions are not enough to cure a genetic brain disorder.
The purified extracted DNA from the affected brain cell can make us understand about the region or base pairs of the mutated DNA which are responsible for coding the abnormal proteins to cause autism.